Pain caused by sin

And when the woman saw that the tree was good for food, and that it was pleasant to the eyes, and a tree to be desired to make one wise, she took of the fruit of it and did eat, and gave also unto her husband with her; and he did eat. And the eyes of them both were opened, and they knew that they were naked; and they sewed fig leaves together, and made themselves aprons. (Genesis 3:6-7)

And Cain talked with Abel his brother: and it came to pass, when they were in the field, that Cain rose up against Abel his brother, and slew him. (Genesis 4:8)

Good understanding gives favor, but the way of transgressors is hard. (Proverbs 13:15)

There is no peace, says the LORD, unto the wicked. (Isaiah 48:22)

Behold, the LORD’s hand is not shortened, that it cannot save; neither his ear heavy, that it cannot hear: But your iniquities have separated between you and your God, and your sins have hid his face from you, that he will not hear. (Isaiah 59:1-2)

For the wages of sin is death; but the gift of God is eternal life through Jesus Christ our Lord. (Romans 6:23)